The Vitl Nutrition Team / 28 Aug 2025
A groundbreaking study published in Nature Medicine has just thrown a nutritional curveball that's making headlines across the UK. Researchers at UCL did something brilliantly simple yet revolutionary: they fed people two diets with identical calories and macronutrients - one packed with ultra-processed foods (UPFs), the other with minimally processed whole foods. ( Nature Medicine )
The result? People eating the whole food diet lost twice as much weight even though they were eating the exact same amount of calories and nutrients on paper. It's like finding out that two identical-looking £20 notes have completely different spending power!
Ultra-processed foods are basically anything that's been through the nutritional equivalent of a witness protection program - so transformed that you'd never recognize the original ingredients. Think ready meals, protein bars, flavoured yoghurts, breakfast cereals, and yes, even some of those "healthy" plant-based meat alternatives.
Here's the kicker:about 60% of the average UK diet is now UPFs ( British Journal of Nutrition). That's like having a house that's 60% made of cardboard instead of bricks - it might look the same from the outside, but the foundation is completely different!
For busy professionals juggling deadlines, meetings, and that ever-growing inbox, this research hits different. We've been told that "calories in, calories out" is the golden rule - that a calorie is a calorie whether it comes from a homemade smoothie or a shop-bought one.
But our bodies are more sophisticated than a simple calculator. When you eat that ultra-processed "healthy" bar, your body has to work less to break it down and absorb it. Sounds efficient, right? Wrong! This actually means:
It's like the difference between climbing stairs and taking a lift - both get you to the same floor, but one gives your body a much better workout!
Let's be honest - meal prep on a Sunday evening after a long week hits about as hard as a soggy sandwich. The convenience of UPFs isn't just appealing; it's often essential for survival in our fast-paced world. But this research suggests that reaching for that convenient option might be the nutritional equivalent of putting regular petrol in a sports car - it'll run, but not optimally.
Those afternoon energy crashes? The 4pm sweet tooth that has you eyeing the office biscuit tin? The fact that you're hungry an hour after that "nutritionally complete" lunch? This study might just have explained why.
Before you panic-throw every convenient food in your kitchen into the bin (please don't, we're in a cost-of-living crisis!), remember that small changes can make big differences:
Instead of: Ultra-processed protein bars
Try: A handful of nuts with an apple (nature's original grab-and-go combo)
Instead of: Flavoured yoghurt with "real fruit pieces"
Try: Plain Greek yoghurt with actual berries (revolutionary, we know!)
Instead of: Ready-made smoothies
Try: Frozen fruit + milk/water + 1 minute with a blender
Instead of: Instant oats with flavouring
Try: Rolled oats soaked overnight with real vanilla and cinnamon
Here's where we get a bit science-y but stay with us - it's fascinating! The study used a crossover design, meaning the same people ate both diets, making it incredibly robust. When the exact same humans ate minimally processed foods, their bodies simply worked differently at a metabolic level.
This isn't about demonising every processed food (let's be real, even chopping an apple is technically processing!). It's about understanding that how our food is made matters just as much as what's in it.
The beautiful thing about this research is that it puts power back in your hands. You don't need to count calories obsessively or follow complex diet rules. Sometimes the simplest approach - choosing foods that look like they came from nature rather than a laboratory - can be the most effective.
Your body is an incredibly sophisticated machine that's been fine-tuned over thousands of years to work with real food. When we give it ultra-processed alternatives, it's like trying to run modern software on an old computer - technically possible, but not exactly optimal performance.
At Vitl, we've always believed that nutrition should work with your body, not against it. While we can't always avoid the convenience of processed foods (and shouldn't feel guilty about it!), this research reinforces why we focus on bioavailable forms of nutrients that your body recognises and can actually use effectively.
Think of it this way: if you're going to supplement, choose forms that work like whole foods in your body rather than synthetic shortcuts. Your metabolism will thank you, your energy levels will stabilise, and you might just find that 3pm slump becomes a thing of the past.
Ready to give your body the fuel it actually recognises?
Christina
#LiveLifeBetter
Complete our online health quiz at https://vitl.com/consultation, to unlock personalised nutrition recommendations delivered to your door. To check out our new AI Calorie Tracking App, Calio, go to theApp Store.